Here is another part to the yes answer. You can also run a wiki with LAMP, MAMP, and WAMP. The first letter of those three words stands for the operating system the rest is Apache, PHP, and MySQL. MAMP on my Mac runs just like an application you can open and quit it just like any other applications.
These kind of packages are for people to do development work and not for serving the websites to the world. I use MAMP to server a BLOG for myself that I use as a journal. You can do the same for a wiki if that is what you were looking for.